基因名：
ATG4C
产品别名：
APG4-C； APG4C； AUTL1； AUTL3； HsAPG4C； ATG4C； autophagy related 4C cysteine peptidase； autophagy related 4C cysteine peptidase； cysteine protease ATG4C； APG4 autophagy 4 homolog C； ATG4 autophagy related 4 homolog C； AUT-like 1, cysteine endopeptidase； AUT-like 3 cysteine endopeptidase； autophagin-3； autophagy-related cysteine endopeptidase 3； autophagy-related protein 4 homolog C； epididymis secretory sperm binding protein； 磷酸化自噬相关蛋白4C； 自噬相关蛋白4C；
背景信息：
Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.
