基因名:
Spred1
产品别名:
5730461F13Rik; AL024345; AW047647; Spred1; sprouty protein with EVH-1 domain 1, related sequence; sprouty protein with EVH-1 domain 1, related sequence; sprouty-related, EVH1 domain-containing protein 1; sprouty-related protein 1 with EVH-1 domain; SPRED1蛋白;
背景信息:
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]