基因名：
MRGPRF
产品别名：
GPR140； GPR168； MRGF； RTA； MRGPRF； MAS related GPR family member F； MAS related GPR family member F； mas-related G-protein coupled receptor member F； G protein-coupled receptor MrgF； G-protein coupled receptor 140； G-protein coupled receptor 168； MAS-related GPR, member F； Mas-related G protein-coupled receptor F； mas-related G protein-coupled MRGF； mas-related gene F protein； seven transmembrane helix receptor； G蛋白偶联受体RTA蛋白；
背景信息：
MRGF is a 343 amino acid multi-pass membrane protein that functions as an orphan receptor. MRGF belongs to the G-protein coupled receptor 1 family and Mas subfamily, and is thought to have a role in pain sensation and modulation by regulating nociceptor function. The gene encoding MRGF maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
