基因名:
ACVR1C
产品别名:
ACVRLK7; ALK7; ACVR1C; activin A receptor type 1C; activin A receptor type 1C; activin receptor type-1C; ACTR-IC; ALK-7; activin A receptor, type IC; activin receptor type IC; activin receptor-like kinase 7; 激活素A受体ⅠC(ACVR1C); 激活素受体1C;
背景信息:
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.