基因名:
NCOA7
产品别名:
ERAP140; ESNA1; NCOA7-AS; Nbla00052; Nbla10993; TLDC4; dJ187J11.3; NCOA7; nuclear receptor coactivator 7; nuclear receptor coactivator 7; nuclear receptor coactivator 7; 140 kDa estrogen receptor-associated protein; TBC/LysM-associated domain containing 4; estrogen nuclear receptor coactivator 1; estrogen receptor associated protein 140 kDa; putative protein product of Nbla00052; putative protein product of Nbla10993; 核受体共激活因子7;
背景信息:
NCoA-7 is a 942 amino acid nuclear protein that enhances nuclear receptor transcriptional activities and coactivates several nuclear receptors including PPAR©, ERå, TR∫1 and RARå. Highly expressed in brain and weakly expressed in pancreas, bladder, ovary, spinal cord, prostate, mammary gland, ovary, uterus and stomach, NCoA-7 is a member of the OXR1 family and contains one LysM repeat and a TLD domain. Six NCoA-7 isoforms are known to exist due to alternative splicing events, and the gene encoding NCoA-7 maps to human chromosome 6q22.31 and mouse chromosome 10 A4.