基因名:
RIMS4
产品别名:
C20orf190; RIM 4; RIM-4; RIM4; RIM4-gamma; RIM4gamma; RIMS4; regulating synaptic membrane exocytosis 4; regulating synaptic membrane exocytosis 4; regulating synaptic membrane exocytosis protein 4; RIM4 gamma; rab3-interacting molecule 4; 神经元突触膜胞外分泌调节蛋白4;
背景信息:
Rim4 (Rab 3 interacting molecule 4), also known as Rim4 or regulating synaptic membrane exocytosis protein 4, is a 269 amino acid protein that localizes to the cell junction and regulates synaptic membrane exocytosis. Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis. Rab 3 functions in an inhibitory capacity by controlling the recruitment of secretory vesicles into a releasable pool at the plasma membrane. Rim (Rab 3 interacting molecule), a putative effector protein for Rab 3 proteins, is thought to regulate neutrotransmitter release through its interaction with Rab 3 and other synaptic proteins.