基因名:
Ticam2
产品别名:
B430113A10; TICAM-2; TRAM; Tirp; Trif; Ticam2; toll-like receptor adaptor molecule 2; toll-like receptor adaptor molecule 2; TIR domain-containing adapter molecule 2; TIR domain-containing adapter protein; TRIF-related adapter molecule TRAM; TRIF-related adaptor molecule; Toll-interleukin I receptor domain (TIR)-containing adaptor molecule (TICAM) 2; toll/interleukin-1 receptor domain-containing protein; Toll样受体衔接分子2(TICAM2); Toll样受体衔接蛋白TICAM2;
背景信息:
This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway. [provided by RefSeq, Nov 2010]