基因名:
MAPK15
产品别名:
ERK7; ERK8; MAPK15; mitogen-activated protein kinase 15; mitogen-activated protein kinase 15; mitogen-activated protein kinase 15; ERK-7; ERK-8; MAP kinase 15; MAPK 15; extracellular regulated kinase 8 delta; extracellular signal-regulated kinase 7; extracellular signal-regulated kinase 8; 丝裂原活化蛋白激酶15; 磷酸化丝裂原活化蛋白激酶15;
背景信息:
MAPK15 is a 544 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family (MAP kinase subfamily). MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPK15 functions as a catalytic kinase using ATP to produce ADP and a phosphoprotein. A TXY motif, containing one threonine and one tyrosine residue, activates the MAP kinases upon phosphorylation. MAPK15 is a ubiquitously expressed protein with highest expression found in lung and kidney.