基因名：
IFNL3
产品别名：
IFN-lambda-3； IFN-lambda-4； IL-28B； IL-28C； IL28B； IL28C； IFNL3； interferon lambda 3； interferon lambda 3； interferon lambda-3； cytokine Zcyto22； interferon, lambda 4； interleukin-28B； interleukin-28C； 白介素28B(IL28B)；
背景信息：
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
