基因名：
IFNL1
产品别名：
IL-29； IL29； IFNL1； interferon lambda 1； interferon lambda 1； interferon lambda-1； IFN-lambda-1； cytokine Zcyto21； interleukin 29 (interferon, lambda 1)； interleukin-29； 白介素28B； 白介素29(IL29)； 白介素29(IL29)真核蛋白； 白细胞介素29；
背景信息：
Interleukin-29 (IL-29) is a secreted protein which belongs to the IL-28/IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10R beta) and an orphan class II receptor chain, designated IL-28R alpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
