基因名：
SUMO4
产品别名：
IDDM5； SMT3H4； SUMO-4； dJ281H8.4； SUMO4； small ubiquitin like modifier 4； small ubiquitin like modifier 4； small ubiquitin-related modifier 4； SMT3 suppressor of mif two 3 homolog 2； SMT3 suppressor of mif two 3 homolog 4； insulin-dependent diabetes mellitus 5； small ubiquitin-like modifier 4 protein； 小泛素样修饰蛋白4；
背景信息：
This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq, Jul 2008]
