基因名:
SPANXB1
产品别名:
B1; CT11.2; SPANX-B; SPANXB; SPANXB2; SPANXF1; SPANXF2; SPANXB1; SPANX family member B1; SPANX family member B1; sperm protein associated with the nucleus on the X chromosome B1; SPANX family member B/F; SPANX family member F1; SPANX family, member B2; SPANX family, member F2; cancer/testis antigen 11.2; cancer/testis antigen family 11, member 2; nuclear-associated protein SPAN-Xb; nuclear-associated protein SPAN-Xf; sperm protein associated with the nucleus on the X chromosome B/F; sperm protein associated with the nucleus, X chromosome, family member B1; 肿瘤/睾丸抗原11.2;
背景信息:
A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.