ISS610 is a STAT3 inhibitor. Aberrant activation of oncogenic signal transducer and activator of transcription 3 (STAT3) protein signaling pathways has been extensively implicated in human cancers. References: Shahani VM, Yue P, Fletcher S, Sharmeen S, Sukhai MA, Luu DP, Zhang X, Sun H, Zhao W, Schimmer AD, Turkson J, Gunning PT. Design, synthesis, and in vitro characterization of novel hybrid peptidomimetic inhibitors of STAT3 protein. Bioorg Med Chem. 2011 Mar 1;19(5):1823-38. doi: 10.1016/j.bmc.2010.12.010. Epub 2010 Dec 9. PubMed PMID: 21216604; PubMed Central PMCID: PMC3151534.
纯度:≥98%
CAS:725233-55-6