Smilagenin, formerly known as PYM50028, is an orally bioavailable, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. References: Li J, Xia Z, Sun X, Zhang R, Huang G, Hickling R, Xia Z, Hu Y, Zhang Y. Reversal of dopamine neurons and locomotor ability degeneration in aged rats with smilagenin. Neuroscience. 2013 Aug 15;245:90-8. doi: 10.1016/j.neuroscience.2013.04.028. Epub 2013 Apr 23. PubMed PMID: 23624370.
纯度:≥98%
CAS:126-18-1