SR1555 is an inverse agonist of RORgamma which suppresses TH17 differentiation and stimulated iTreg cells, repressing the expression of RORgamma while leading to increased expression of FGF21 and adipoQ, thereby reducing body weight and improving insulin sensitivity. References: Chang MR, He Y, Khan TM, Kuruvilla DS, Garcia-Ordonez R, Corzo CA, Unger TJ, White DW, Khan S, Lin L, Cameron MD, Kamenecka TM, Griffin PR. Antiobesity Effect of a Small Molecule Repressor of RORγ. Mol Pharmacol. 2015 Jul;88(1):48-56. doi: 10.1124/mol.114.097485. Epub 2015 Apr 22. PubMed PMID: 25904554; PubMed Central PMCID: PMC4468634.

纯度：≥98%

CAS：1386439-51-5