Mepacrine is an acridine analogue formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2. References: Park S, Oh AY, Cho JH, Yoon MH, Woo TG, Kang SM, Lee HY, Jung YJ, Park BJ. Therapeutic Effect of Quinacrine, an Antiprotozoan Drug, by Selective Suppression of p-CHK1/2 in p53-Negative Malignant Cancers. Mol Cancer Res. 2018 Mar 15. doi: 10.1158/1541-7786.MCR-17-0511. [Epub ahead of print] PubMed PMID: 29545477.
纯度:≥98%
CAS:83-89-6