HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor. It acts by improving memory in control and memory-deficient mice models. References: Albiston AL, Pham V, Ye S, Ng L, Lew RA, Thompson PE, Holien JK, Morton CJ, Parker MW, Chai SY. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78(4):600-7. doi: 10.1124/mol.110.065458. Epub 2010 Jul 13. PubMed PMID: 20628006.
纯度:≥98%
CAS:332164-34-8