Helenalin is a sesquiterpene lactone with anti-inflammatory effects. Helenalin inhibits gene expression mediated by NF-κB and can modify sulfhydryl groups of cysteine residues. It also suppresses the proliferation of cancer cells through the prevention of signaling through NF-κB. References: Widen JC, Kempema AM, Baur JW, Skopec HM, Edwards JT, Brown TJ, Brown DA, Meece FA, Harki DA. Helenalin Analogues Targeting NF-κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles. ChemMedChem. 2018 Feb 20;13(4):303-311. doi: 10.1002/cmdc.201700752. Epub 2018 Jan 19. PubMed PMID: 29349898; PubMed Central PMCID: PMC5894512.
纯度:≥98%
CAS:6754-13-8