H8-A5 is a novel HDAC8 inhibitor. H8-A5 is selective for HDAC8 over HDAC 1/4 and shows antiproliferation activity in MDA-MB-231 cancer cells. References: Hou X, Du J, Liu R, Zhou Y, Li M, Xu W, Fang H. Enhancing the Sensitivity of Pharmacophore-Based Virtual Screening by Incorporating Customized ZBG Features: A Case Study Using Histone Deacetylase 8. J Chem Inf Model. 2015 Apr 27;55(4):861-71. doi: 10.1021/ci500762z. Epub 2015 Mar 16. PubMed PMID: 25757142.
纯度:≥98%
CAS:423731-10-6