GW 9578 is a potent agonist of PPARα that activates the murine and human receptors with EC50 of 0.005 and 0.05 μM. GW 9578 is a potent lipid lowering agent that may reduce insulin resistance. References: Brown PJ, Winegar DA, Plunket KD, Moore LB, Lewis MC, Wilson JG, Sundseth SS, Koble CS, Wu Z, Chapman JM, Lehmann JM, Kliewer SA, Willson TM. A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity. J Med Chem. 1999 Sep 23;42(19):3785-8. PubMed PMID: 10508427.
纯度:≥98%
CAS:247923-29-1