Suprafenacine is a novel cell permeable selective inhibitor of cancer cell proliferation, binding microtubules at the colchicine-binding site and inhibiting polymerization, leading to G2/M cell cycle arrest and cell death via a mitochondria-mediated apoptotic pathway. References: Choi BH, Chattopadhaya S, Thanh le N, Feng L, Nguyen QT, Lim CB, Harikishore A, Nanga RP, Bharatham N, Zhao Y, Liu X, Yoon HS. Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization. PLoS One. 2014 Oct 29;9(10):e110955. doi: 10.1371/journal.pone.0110955. eCollection 2014. PubMed PMID: 25354194; PubMed Central PMCID: PMC4212991.

纯度：≥98%

CAS：1477482-50-0