SZV558 is a potent inhibitor of both rodent and human MAO-B, proved to be safe in high doses with no hERG and mutagenic activities and demonstrated neuroprotection in an in vivo chronic model of PD. References: Baranyi M, Porceddu PF, Goloncsér F, Kulcsár S, Otrokocsi L, Kittel A, Pinna A, Frau L, Huleatt PB, Khoo ML, Chai CL, Dunkel P, Mátyus P, Morelli M, Sperlágh B. Novel (Hetero)arylalkenyl propargylamine compounds are protective in toxin-induced models of Parkinson's disease. Mol Neurodegener. 2016 Jan 13;16. doi: 10.1186/s13024-015-0067-y. PubMed PMID: 26758813; PubMed Central PMCID: PMC4711075.
纯度:≥98%
CAS:1648929-13-8