GRI977143 is a selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM). GRI977143 does not activate other LPA GPCRs at concentrations up to 10 μM. References: Lin KH, Ho YH, Chiang JC, Li MW, Lin SH, Chen WM, Chiang CL, Lin YN, Yang YJ, Chen CN, Lu J, Huang CJ, Tigyi G, Yao CL, Lee H. Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis. Sci Rep. 2016 May 31;6:27050. doi: 10.1038/srep27050. PubMed PMID: 27244685; PubMed Central PMCID: PMC4886675.
纯度:≥98%
CAS:325850-81-5