GJ-071 is a Nonsense suppressor. Nonsense suppressors (NonSups) induce “readthrough”, i.e., the selection of near cognate tRNAs at premature termination codons and insertion of the corresponding amino acid into nascent polypeptide. References: Lavin MF. Generating SM(a)RTer compounds for translation termination suppression in A-T and other genetic disorders. Mol Ther. 2013 Sep;21(9):1650-2. doi: 10.1038/mt.2013.177. PubMed PMID: 24008619; PubMed Central PMCID: PMC3776641.

纯度：≥98%

CAS：1216676-34-4