NSC19630, formerly known as MIRA-1, is a potent and selective WRN helicase inhibitor with activity against human normal and cancer cells via a caspase-9-dependent apoptosis. References: Bou-Hanna C, Jarry A, Lode L, Schmitz I, Schulze-Osthoff K, Kury S, Bezieau S,
Mosnier JF, Laboisse CL. Acute cytotoxicity of MIRA-1/NSC19630, a mutant
p53-reactivating small molecule, against human normal and cancer cells via a
caspase-9-dependent apoptosis. Cancer Lett. 2015 Apr 10;359(2):211-7. doi:
10.1016/j.canlet.2015.01.014. Epub 2015 Jan 21. PubMed PMID: 25617798.
纯度:≥98%
CAS:72835-26-8