FiVe1 is a novel, selective and potent vimentin (VIM) ligand that inhibits the growth of mesenchymally transformed breast cancer cells and soft tissue sarcomas of diverse histological subtypes.
References: Bollong MJ, Pietila M, Pearson AD, Sarkar TR, Ahmad I, Soundararajan R, Lyssiotis CA, Mani SA, Schultz PG, Lairson LL. A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9903-E9912. doi: 10.1073/pnas.1716009114. Epub 2017 Oct 30. PubMed PMID: 29087350; PubMed Central PMCID: PMC5699095.
纯度:≥98%
CAS:932359-76-7