pBBG is a glyoxalase 1 (Glo1) inhibitor, decreasing alcohol drinking in nondependent mice. References: Barkley-Levenson AM, Lagarda FA, Palmer AA. Glyoxalase 1 (GLO1) Inhibition or Genetic Overexpression Does Not Alter Ethanol's Locomotor Effects: Implications for GLO1 as a Therapeutic Target in Alcohol Use Disorders. Alcohol Clin Exp Res. 2018 May;42(5):869-878. doi: 10.1111/acer.13623. Epub 2018 Apr 18. PubMed PMID: 29532486; PubMed Central PMCID: PMC5915917.
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CAS:166038-00-2