Eribaxaban, formerly known as PD348292 or PD0348292, is an orally bioavailable factor Xa inhibitor under development for the treatment and prevention of thrombotic disorders. PD0348292 inhibited arterial thrombosis comparable to aspirin plus clopidogrel. Perfusion chamber methodology may be useful in predicting in-vivo antithrombotic efficacy. References: Cohen AT, Boyd RA, Mandema JW, Dicarlo L, Pak R; A5571010 Investigators. An adaptive-design dose-ranging study of PD 0348292, an oral factor Xa inhibitor, for thromboprophylaxis after total knee replacement surgery. J Thromb Haemost. 2013 Aug;11(8):1503-10. doi: 10.1111/jth.12328. PubMed PMID: 23782955.
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CAS:536748-46-6