Description: Tolazoline sulfate is a potent, non-selective competitive α-adrenergic receptor antagonist. Tolazoline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN). Tolazoline has moderate alpha-adrenergic blocking activity and has histamine agonist activity. Tolazoline usually reduces pulmonary arterial pressure and vascular resistance.
References: J Cardiovasc Pharmacol. 1998 May;31(5):721-33; Ann Thorac Surg. 2006 Jan;81(1):125-31.
Related CAS#: 59-98-3 (free base)
纯度:≥98%