TP0438836 is a potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor for the treatment of type 2 diabetes. TP0438836 showed IC50 28nM and 7 nM for hSGLT1 and hSGLT2 resepctively. References: Kuroda S, Kobashi Y, Oi T, Amada H, Okumura-Kitajima L, Io F, Yamamto K, Kakinuma H. Discovery of a potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor (TP0438836) for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2018 Dec 1;28(22):3534-3539. doi: 10.1016/j.bmcl.2018.09.035. Epub 2018 Sep 29. PubMed PMID: 30297284.

纯度：≥98%

CAS：957772-01-9