Description: Enalapril sodium (also known as MK-421 sodium) is a potent nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor widely used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure. Enalapril has been used to study diabetic angiopathy in diabetic rats and inhibition of ACE in hog plasma (I50=1.2nM). Enalapril treatment abolishes the deleterious effects of eNOS deficiency on blood pressure (BP), atherosclerosis, and kidney dysfunction in mice.

References: Clin Pharm. 1985;4(1):27-40; J Clin Invest. 2000;105(4):451-8; Pharmacol Res. 2011;64(5):482-92.

Related CAS#: 84680-54-6 (Enalaprilat Dihydrate); 75847-73-3 (Enalapril free base); 149404-21-7 (Enalapril sodium); 349554-02-5 (Enalapril D5 maleate); 690655-41-5 (NCX899, a NO-releasing derivative of enalapril)

纯度：≥98%

CAS：149404-21-7