Monocrotaline(Crotaline)

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CAS NO:	315-22-0
规格:	≥98%

包装与价格：

包装	价格(元)
25mg	询价
50mg	询价
100mg	询价
250mg	询价
500mg	询价
1g	询价
2g	询价

Monocrotaline (NSC-28693; Crotaline) is a naturally occuring pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant, exhibiting dose-dependent cytotoxicity and causing pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. However, it also has therapeutic potential against hepatocellular carcinoma. It acts against p53, HGF and TREM1 proteins, which play a threatening role in causing hepatocellular carcinoma. It is a novel scaffold for liver cancer with superior efficacy and lesser side effects. A

理化性质和储存条件

Molecular Formula: C16H23NO6;

Exact Mass: 325.1525
Molecular Weight: 325.36
Synonym: NSC-28693; Crotaline; NSC 28693; NSC28693

Chemical Name: 20-Norcrotalanan-11,15-dione, 14,19-dihydro-12,13-dihydroxy-, (13-alpha,14-alpha)- (9CI)

InChi Key: QVCMHGGNRFRMAD-XFGHUUIASA-N

InChi Code: InChI=1S/C16H23NO6/c1-9-13(18)23-11-5-7-17-6-4-10(12(11)17)8-22-14(19)16(3,21)15(9,2)20/h4,9,11-12,20-21H,5-8H2,1-3H3/t9-,11+,12+,15+,16-/m0/s1

SMILES Code: O=C(O[C@]1([H])CCN2[C@]1([H])C(CO3)=CC2)[C@H](C)[C@@](C)(O)[C@@](C)(O)C3=O