EC17 sodium (Folate-FITC) is a fluorescein
isothiocyanate (FITC) conjugated folic acid with potential
antineoplastic activity. It also acts as a FRα-targeting agent that
fluoresces at 500nm. EC17 is conjugate consisting of fluorescein
isothiocyanate (FITC) conjugated with folate with potential
antineoplastic activity. Folate-FITC binds to folate receptors, which
are overexpressed on the surfaces of many cancer cells including kidney
and ovarian cancer cells. Once bound to the cancer cell through the
folate moiety of the conjugate, curculating anti-fluorescein
antibodies.may recognize and bind to the FITC moiety, resulting in
antibody-dependent cellular cytotoxicity.
纯度:≥98%
CAS:910661-33-5