Levadopa Related Compound A is the 6-hydroxy analogue of the amino acid L-DOPA with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase. References: Luurtsema G, Boersma HH, Schepers M, de Vries AMT, Maas B, Zijlma R, de Vries EFJ, Elsinga PH. Improved GMP-compliant multi-dose production and quality control of 6-[(18)F]fluoro-L-DOPA. EJNMMI Radiopharm Chem. 2017;1(1):7. doi: 10.1186/s41181-016-0009-1. Epub 2016 Apr 4. PubMed PMID: 29564384; PubMed Central PMCID: PMC5843807.
纯度:≥98%
CAS:27244-64-0