DS28120313 is a potent hepcidin production inhibitor. 32 (DS28120313) showed serum hepcidin-lowering effects in an interleukin-6-induced acute inflammatory mouse model. References: Fukuda T, Goto R, Kiho T, Ueda K, Muramatsu S, Hashimoto M, Aki A, Watanabe K, Tanaka N. Discovery of DS28120313 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4,6-disubstituted indazole derivatives. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5252-5257. doi: 10.1016/j.bmcl.2017.10.031. Epub 2017 Oct 16. PubMed PMID: 29079471.
纯度:≥98%
CAS:2146177-09-3