Dihydrexidine is a dopamine D1 receptor agonist potentially for the treatment of schizotypal personality disorder. A single 20 mg dose of the full D1 dopamine agonist dihydrexidine (DAR-0100) has been shown to increase prefrontal perfusion in schizophrenia, and is safe and tolerated in patients with schizophrenia. References: Mu Q, Johnson K, Morgan PS, Grenesko EL, Molnar CE, Anderson B, Nahas Z, Kozel FA, Kose S, Knable M, Fernandes P, Nichols DE, Mailman RB, George MS. A single 20 mg dose of the full D1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia. Schizophr Res. 2007 Aug;94(1-3):332-41. PubMed PMID: 17596915.
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CAS:123039-93-0