Dihydrocelastrol, formerly known as DHCE and Triptohypol C, is synthesized by hydrogenation of celastrol, which is a treterpene extracted from Chinese medicinal plant Tripterygium regelii. Dihydrocelastrol could inhibit cell proliferation and promote apoptosis through caspase-dependent way in vitro. DHCE could inhibit cellular proliferation and induce cell apoptosis in myeloma cells mediated through different mechanisms, possibly through inhibiting the IL-6/STAT3 and ERK1/2 pathways. And it may provide a new therapeutic option for MM patients. References: Woo SG, Lee SM, Lee SY, Lim KH, Ha EJ, Kim SH, Eom YB. The effectiveness of anti-biofilm and anti-virulence properties of dihydrocelastrol and dihydrocelastryl diacetate in fighting against methicillin-resistant Staphylococcus aureus. Arch Microbiol. 2017 May 9. doi: 10.1007/s00203-017-1386-x. [Epub ahead of print] PubMed PMID: 28487997.

纯度：≥98%

CAS：193957-88-9