LY 231617 is a potent antioxidant that readily crosses the blood-brain barrier. LY 231617 significantly reduces ischemia-induced or hydrogen peroxide-induced neuronal damage and inhibits lipid peroxidation (IC50 = 22 μM). LY 231617 prevents nuclear translocation of activated NF-κB in hippocampal neurons. References: Shani V, Bromberg Y, Sperling O, Zoref-Shani E. Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia. J Mol Neurosci. 2009 Jan;37(1):50-9. doi: 10.1007/s12031-008-9113-3. Epub 2008 Jun 27. PubMed PMID: 18584337.

纯度：≥98%

CAS：93811-58-6