Nevanimibe HCl (also known as PD-132301 hydrochloride and ATR-101 hydrochloride), the hydrochloride salt of Nevanimibe, is a novel, selective and potent acyl-coenzyme A: cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. It inhibits ACAT2 with an EC50of 368 nM.
理化性质和储存条件
| Molecular Weight: 458.08
Formula: C27H40ClN3O
CAS No.: 133825-81-7
SMILES: O=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C.[H]Cl |
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| Storage | -20℃ for 3 years in powder form |
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| -80℃ for 2 years in solvent |
| Technical Information | PD-132301 hydrochloride; PD132301 hydrochloride; PD 132301 hydrochloride; ATR-101 hydrochloride;ATR 101 hydrochloride;ATR101 hydrochloride; |
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