Dehydrosertindole is a metabolite of Sertindole, an antipsychotic agent that is used to treat patients with schizophrenia. Dehydrosertindole inhibits limbic dopamine function and has high affinity for dopamine D2 receptors, serotonin 5-hydroxytryptamine (5-HT) 2 receptors and α1-adrenergic receptors. References: Bundgaard C, Larsen F, Kreilgaard M, Brennum LT, Olsen CK. Pharmacokinetics of sertindole and its metabolite dehydrosertindole in rats and characterization of their comparative pharmacodynamics based on in vivo D2 receptor occupancy and behavioural conditioned avoidance response. Biopharm Drug Dispos. 2009 May;30(4):209-20. doi: 10.1002/bdd.656. PubMed PMID: 19475539.

纯度：≥98%

CAS：173294-84-3