Centrinone (LCR263; LCR-263; LCR 263) is a novel and potent inhibitor of polo-like kinase 4 (PLK4) with potential antineoplastic activity. It inhibits PLK4 with a Ki of 0.16 nM and shows >1000-fold selectivity for PLK4 over Aurora A and Aurora B.

纯度：≥98%

CAS：1798871-30-3