CGP 55845 HCl is a potent, selective GABAB receptor antagonist (IC50 = 5 nM) that prevents agonist binding (pKi = 8.35) and inhibits GABA and glutamate release (pEC50 are 8.08 and 7.85 respectively). References: Gillani Q, Ali M, Iqbal F. Effect of GABA(B) receptor antagonists (CGP 35348 and CGP 55845) on serum interleukin 6 and 18 concentrations in albino mice following neonatal hypoxia ischemia insult. Pak J Pharm Sci. 2016 Sep;29(5):1503-1508. PubMed PMID: 27731803.

纯度：≥98%

CAS：149184-22-5