CMF-019 is a small molecule agonist with G protein bias. CMF-019 is the first potent biased small molecule identified at the apelin receptor and increases cardiac contractility in vivo. References: Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP. Cardiac action of the first G protein biased small molecule apelin agonist. Biochem Pharmacol. 2016 Sep 15;116:63-72. doi: 10.1016/j.bcp.2016.07.018. Epub 2016 Jul 27. PubMed PMID: 27475715; PubMed Central PMCID: PMC5012889.
纯度:≥98%
CAS:1586787-08-7