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(S)-Baclofen
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:66514-99-6
规格:≥98%

Description: (S)-Baclofen, the S-isomer of baclofen(also known as STX 209) which is a derivative of gamma-aminobutyric acid and a selective GABAB receptor agonist.primarily used to treat spasticity. Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing It acts at spinal and supraspinal sites, reducing excitatory transmission. GABAB receptors are metabotropic receptors which produce slow inhibitory signals. (S)-Baclofen has effects on excitation in the ascending auditory pathway making it a potential treatment for hyperactive auditory disorders such as tinnitus and hyperacusis.

References: Neuroscience. 2014 Jan 31;258:410-21. doi: 10.1016/j.neuroscience.2013.11.032. Epub 2013 Nov 26. PubMed PMID: 24291770; J Neurochem. 1986 Sep;47(3):898-903; Lancet. 1984 May 12;1(8385):1078.

Related CAS No.: 63701-55-3 [(R)-Baclofen HCl]

纯度:≥98%

CAS:66514-99-6

 
 
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