2-Amino-2-(p-tolyl)acetic acid 可用于优化叠氮骨架,是 1,3,4- 噻二唑类化合物的中间体。1,3,4- 噻二唑类化合物具有出潜在的抗癌活性,并对谷氨酰胺酶有抑制作用。
Cas No. | 13227-01-5 |
分子式 | C9H11NO2 |
分子量 | 165.19 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI)[1][2]. [1]. Kalie A M, et al. Cytosolic Delivery of Proteins by Bioreversible Esterification. JAmChem. 2017. 139(41):14396-14398. [2]. Finlay MRV, et al. Preparation of 1,3,4-thiadiazole compounds and their use in treating cancer: World Intellectual Property Organization, WO2017093301[P]. 2017-06-08. |