Nomegestrol 是一种有效的口服孕激素，作为选择性全孕酮受体激动剂，对大鼠子宫孕酮受体的 Kd 为 5.44 nM，具有中等的抗雄激素活性和强的抗雌激素活性。
| Cas No. | 58691-88-6 |
| 别名 | 诺美孕酮 |
| Canonical SMILES | O=C(C)[C@@]1(O)CC[C@@]2([H])[C@]3([H])C=C(C)C4=CC(CC[C@]4([H])[C@@]3([H])CC[C@@]21C)=O |
| 分子式 | C21H28O3 |
| 分子量 | 328.5 |
| 溶解度 | Chloroform: soluble,DMSO: slightly soluble,Methanol: slightly soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Nomegestrol is a derivative of 19-norprogesterone.1It increases nuclear levels of the progesterone receptor in rat uterus when administered at a dose of 1 mg/animal. 1.Botella, J., Duc, I., Delansorne, R., et al.Structure-activity and structure-affinity relationships of 19-nor-progesterone derivatives in rat uterusJ. Endocrinol. Invest.13(11)905-910(1990) |
