GSK251 是一种高效、高选择性、口服生物利用度的 PI3Kδ 抑制剂，具有新颖的结合模式。
| Cas No. | 2125968-05-8 |
| 分子式 | C29H37FN6O4S |
| 分子量 | 584.71 |
| 溶解度 | DMSO : 62.5 mg/mL (106.89 mM; ultrasonic and warming and heat to 60℃) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode. [1]. Down K, et al. Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode. J Med Chem. 2021 Sep 23;64(18):13780-13792. |
