An intermediate in the synthesis of sildenafil
| Cas No. | 139756-22-2 |
| 别名 | 3-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑O-(4-3-D)-嘧啶-5 |
| Canonical SMILES | O=C1N=C(C2=C(OCC)C=CC(S(=O)(Cl)=O)=C2)NC3=C1N(C)N=C3CCC |
| 分子式 | C17H19ClN4O4S |
| 分子量 | 410.9 |
| 溶解度 | Chloroform: 1 mg/ml,DMSO: slightly soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .1It is also a potential impurity found in commercial preparations of sildenafil. 1.Nagaraju, V., Sreenath, D., Rao, J.T., et al.Separation and determination of synthetic impurities of sildenafil (Viagra) by reversed-phase high-performance liquid chromatographyAnal. Sci.19(7)1007-1011(2003) |
