Guvacoline hydrochloride 是可在 Areca triandra 中发现的一种吡啶生物碱，可作为心房和回肠毒蕈碱受体的全激动剂。
| Cas No. | 6197-39-3 |
| 别名 | 去甲槟榔碱 |
| 分子式 | C7H12ClNO2 |
| 分子量 | 177.63 |
| 溶解度 | DMSO : 100 mg/mL (562.97 mM; Need ultrasonic) |
| 储存条件 | 4°C, away from moisture and light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Guvacoline hydrochloride, a pyridine alkaloid found in Areca triandra, can act as a weak full agonist of atrial and ileal muscarinic receptors[1][2]. [1]. Jiao Wu, et al. Tissue-specific and maturity-dependent distribution of pyridine alkaloids in Areca triandra. J Plant Res. 2019 Jul;132(4):531-540.
[2]. M Wolf-Pflugmann, et al. Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester. Arzneimittelforschung. 1989 May;39(5):539-44. |
