A PEGylated building block
| Cas No. | 24991-53-5 |
| 别名 | 聚氧乙烯双胺 |
| Canonical SMILES | NCCOCCOCCN |
| 分子式 | (C2H4O)nC4H12N2O |
| 分子量 | 0 |
| 溶解度 | DMF: 33 mg/ml,DMSO: 33 mg/ml,Ethanol: 33 mg/ml,PBS (pH 7.2): 5 mg/ml |
| 储存条件 | -20буC |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PEG diamine is a PEGylated building block.1,2It has been used as a linker to conjugate folic acid to 1,2-distearoyl-rac-glycero-PE (1,2-DSPE) as a component in the formation of doxorubicin-containing liposomes with anticancer activity.1PEG diamine has also been conjugated to oleanolic acid , which improves oleanolic acid-induced inhibition of cell proliferation by 677-fold in HepG2 hepatocellular carcinoma cells.2 1.Lee, R.J., and Low, P.S.Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitroBiochim. Biophys. Acta1233(2)134-144(1995)
2.Jannus, F., Medina-O’Donnell, M., Rivas, F., et al.A diamine-PEGylated oleanolic acid derivative induced efficient apoptosis through a death receptor and mitochondrial apoptotic pathway in HepG2 human hepatoma cellsBiomolecules10(10)1375(2020) |
